ISoOR is dedicated to advancing knowledge in retinal organoids, providing the latest research insights for scientists and clinicians. These complex, self-forming three-dimensional structures provide highly accurate in vitro models of the human retina, making retinal organoids invaluable tools for investigating vision loss and testing potential regenerative therapies. Through its comprehensive resources on retinal organoids, ISoOR ensures that the community has access to the most up-to-date information. The ISoORalso organizes Organoids conferences centered on retinal organoids, promoting collaboration and discussion among experts. Additionally, ISoOR's Research Highlights feature significant breakthroughs, keeping researchers informed about the latest developments in retinal organoids research. As the field evolves, the integration of CRISPR technology with retinal organoids is opening new doors for modeling hereditary eye diseases and developing patient-specific genetic treatments.
[Stem Cell Research & Therapy] TEffect of haploinsufficiency of the CRX gene on migration and differentiation of photoreceptor cell precursors in human retinal organoids.
[Cell Reports] Based on human retina-like organs, the spatiotemporal dynamics of genomic structure and its relationship with gene expression patterns were elucidated by high-resolution Hi-C mapping, p...
[Cells] The research established a mouse lens-like organoid with optical properties and monitored the spatiotemporal expression of key lens genes Jag1, Pax6, Prox1, Hsf4, and Cryab through multi-omics...