Intestinal Organoids Research, Colon Organoids

Intestinal Organoids

ISoOR is dedicated to providing the most current information about intestinal organoids, making it an essential resource for researchers and healthcare professionals. ISoOR highlights the latest studies and breakthroughs in the field, including advancements in human intestinal organoids for disease modeling, by sharing informative journals. Additionally, ISoOR organizes conferences that serve as a hub for experts to connect, exchange ideas, and collaborate on research initiatives. These intestinal organoid conferences and journals not only promote the sharing of knowledge but also inspire new approaches to understanding and treating gastrointestinal diseases, significantly impacting the future of intestinal health research.

Research Highlights in Intestinal Organoids

Butyrate Reduces Adherent-Invasive E. coli-Evoked Disruption of Epithelial Mitochondrial Morphology and Barrier Function: Involvement of Free Fatty Acid Receptor 3
[Gut Microbes] Mitigating Adherent-Invasive E. coli-Induced Disruption: Butyrate's Impact on Epithelial Mitochondrial Morphology and Barrier Function Involving Free Fatty Acid Receptor 3.

Intestinal Organoids

Dec 15, 2023
Development and Characterization of NILK-2301, a Novel CEACAM5xCD3 κλ Bispecific Antibody for Immunotherapy of CEACAM5-Expressing Cancers
[Journal Of Hematology & Oncology] Development and Characterization of NILK-2301: A Novel CEACAM5xCD3 κλ Bispecific Antibody for the Immunotherapy of Cancers Expressing CEACAM5.

Intestinal Organoids

Dec 12, 2023
IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B
[Cellular and Molecular Gastroenterology and Hepatology] Unveiling Enhanced Facultative Stem Cell State Elicited by IGF2BP1/IMP1 Deletion: A Comprehensive Exploration of Regulatory Mechanisms Involvin...

Intestinal Organoids

Dec 09, 2023
Development of Functional Resident Macrophages in Human Pluripotent Stem Cell-derived Colonic
[Cell Stem Cell] The human colon-like organ derived from pluripotent stem cells can generate pluripotent hematopoietic progenitor cells and resident macrophages in functional tissues.

November, 12, 2023

Nov 12, 2023
Personalized Drug Screening In Patient-Derived Organoids Of Biliary Tract Cancer And Its Clinical Application
[Cell Reports Medicine] New research in BTC reveals how organoids derived from patients` tumors can guide chemotherapy choices. Validated in patient responses, this method offers a precise tool for ta...

Biliary Tract Cancer Organoids

Nov 08, 2023
Potential Application of Intestinal Organoids in Intestinal Diseases
[Stem Cell Reviews and Reports] This review discusses intestinal organoid culture techniques and their application in gastrointestinal disease research. It highlights the role of intestinal epithelial...

Intestinal Organoids

Nov 08, 2023
Unbiased Transcription Factor CRISPR Screen Identifies ZNF800 as Master Repressor of Enteroendocrine Differentiation
[Science] Combining CRISPR and organoid technique unveiled key player in the gut`s hormone orchestra, ZNF800 emerges as a chief repressor in enteroendocrine cell differentiation.

Intestinal Organoids

Oct 26, 2023
Integrative Genome-Scale Analyses Reveal Post-Transcriptional Signatures of Early Human Small Intestinal Development in a Directed Differentiation Organoid Model
[BMC Genomics] Discover the microRNA signatures driving the early development of human small intestine with a novel organoid-based multi-omic study.

Intestinal Organoids

Oct 26, 2023
Genetic Vulnerability to Crohn’s Disease Reveals a Spatially Resolved Epithelial Restitution Program
[Science Translational Medicine] Researchers use organoid models to unravel how a Crohn`s disease risk variant disrupts intestinal healing, shedding light on tissue repair mechanisms.

Intestinal Organoids

Oct 25, 2023