All Organoid Research Models

All Organoid Models

At ISoOR, you can explore the most recent developments in different organoid models, making it an essential hub for researchers and healthcare professionals. ISoOR frequently updates its platform with cutting-edge research findings and organizes conferences dedicated to organoid model studies. ISoOR also shares influential journals to promote collaboration among experts. Moreover, ISoOR's Research Highlights feature significant discoveries from various organoid models, providing our community with concise summaries of the latest advancements in the field. This is particularly crucial as these advanced organoid models are revolutionizing disease modeling, drug discovery, and the promise of personalized medicine.

Research Highlights

Transcriptomic analysis of benign prostatic hyperplasia identifies critical pathways in prostatic overgrowth and 5-alpha reductase inhibitor resistance
[Prostate] The benign prostatic organoid offers a solution to the drug treatment failures of benign prostatic hyperplasia.

Prostate Organoids

Jan 03, 2024
Biochemical and transcriptomic evaluation of a 3D lung organoid platform for pre-clinical testing of active substances targeting senescence
[Respiratory Research] Utilizing Lung Cancer Organoids and Single-Cell Sequencing to Analyze Senescence-Related Processes and Enable Preselection of Various Compounds in Preclinical Studies.

Lung Organoids

Jan 03, 2024
Desulfovibrio vulgaris interacts with novel gut epithelial immune receptor LRRC19 and exacerbates colitis
[Microbiome] Discovery of Targeting DVF-LRRC19 Interaction through Organoid Models as a Novel Therapeutic Strategy for Ulcerative Colitis (UC).

Intestinal Organoids

Jan 03, 2024
Bioengineered Tubular Biliary Organoids
[Advanced Healthcare Materials] Tubular Biliary Organoids Created Through Bioengineering.

Liver Organoids

Dec 21, 2023
Liver organoids cocultured on decellularized native liver scaffolds as a bridging therapy improves survival from liver failure in rabbits
[In Vitro Cellular and Developmental Biology - Animal] Enhancing Rabbit Survival in Liver Failure through Bridging Therapy: Liver Organoids Cocultured on Decellularized Native Liver Scaffolds.

Liver Organoids

Dec 18, 2023
Generation of novel in vitro flexible kidney organoid model to investigate the role of extracellular vesicles in induction of nephrogenesis
[Cell Communication and Signaling] Development of an Innovative In Vitro Flexible Kidney Organoid Model for Exploring the Influence of Extracellular Vesicles on Nephrogenesis Induction.

Kidney Organoids

Dec 18, 2023
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice
[Developmental Cell] Senescent Intestinal Stem Cells Contribute to Cell-Intrinsic Origins of Inflammaging in Mice.

Intestinal Organoids

Dec 18, 2023
Butyrate Reduces Adherent-Invasive E. coli-Evoked Disruption of Epithelial Mitochondrial Morphology and Barrier Function: Involvement of Free Fatty Acid Receptor 3
[Gut Microbes] Mitigating Adherent-Invasive E. coli-Induced Disruption: Butyrate's Impact on Epithelial Mitochondrial Morphology and Barrier Function Involving Free Fatty Acid Receptor 3.

Intestinal Organoids

Dec 15, 2023
Development and Characterization of NILK-2301, a Novel CEACAM5xCD3 κλ Bispecific Antibody for Immunotherapy of CEACAM5-Expressing Cancers
[Journal Of Hematology & Oncology] Development and Characterization of NILK-2301: A Novel CEACAM5xCD3 κλ Bispecific Antibody for the Immunotherapy of Cancers Expressing CEACAM5.

Intestinal Organoids

Dec 12, 2023

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